The effectiveness of Fildena depends on its duration of action. It works best when penile blood fat levels are low. It is recommended to take Fildena 100 tablets 30-60 minutes before sexual activity. It is important to take it on an empty stomach as the effect lasts for about 4 hours. To get the most out of your treatment, it's important to take them for the right amount of time and stop after the recommended period.